Fans must bid farewell to a handful of beloved One Chicago characters from Chicago Fire, Chicago PD, and Chicago Med during the 2025–

2026 network TV season. The good news is that this might not be the end for some of them. Meanwhile, others could be leaving the One

Chicago universe for good, depending on how their respective shows write them out.

 

 

Over the course of the One Chicago franchise’s history (which spans 36 seasons and 728 episodes ahead of the fall 2025 premieres), many actors have come and gone. Whether they were stationed at Firehouse 51, the Intelligence Unit, or Gaffney Chicago Medical Center, each series has suffered its fair share of cast member exits. Now five more will join the list in 2025.

Chicago Med is set to lose only one cast member in season 11 — Marlyne Barrett. But her departure hits different because she is one of the medical drama’s first stars, having played Maggie Lockwood since the pilot. Barrett was only one of three original actors remaining following the Chicago Med season 10 finale. With her exit, the show is down to two.

 

 

The exact motivation behind Barrett’s exit from Chicago Med is currently unknown, as of the writing of this article. All the reports just claimed that the actress is stepping back for personal reasons. It’s also unclear how the NBC TV series will write her character out of the story during the season 11 premiere.

The previous finale of Chicago Med contained no indication that Maggie planned on leaving Gaffney Chicago Medical Center, meaning anything could cause her to say goodbye to her work family in 2025. However, one can rule out Chicago Med killing off Maggie. The medical drama doesn’t typically go down the morbid route while writing out characters (aside from Dr. Ava Bekker).

Plus, it sounds like Chicago Med season 11 will leave the door open for Maggie’s return. The producers reportedly have hope that Barrett will reprise her role as the ED’s charge nurse in later episodes. Ultimately, everything surrounding Barrett’s departure is up in the air. One thing is for certain, though, Barrett won’t appear in the premiere to say farewell to Maggie.